B.Sc.
HONOURS
DISCIPLINE
OF BIOCHEMISTRY AND MOLECULAR BIOLOGY
Molecular
Sciences Bldg 21, James Cook University,
Townsville,
4811, Queensland, Australia
Telephone:
61-7-4781 6265 Fax: 61-7-4781 6078
HONOURS
IN
GENETICS, BIOCHEMISTRY AND MOLECULAR BIOLOGY
|
- The
Department of
Biochemistry and Molecular Biology incorporates the Comparative
Genomics Centre and is one of the most research-active Departments at
James Cook University. Both basic fundamental and applied biotechnology
research are conducted within the department and its research
activities are supported by grants from national and international
funding agencies such as the National Health and Medical Research
Council, Australian Research Council, the March of Dimes Foundation,
Sugar Research and Development Corporation, Welcome Foundation, Clive
and Vera Ramaciotti Foundation as well as industry. These grants
permit the Department to engage in research that is at the cutting edge
of the field and to provide a vibrant and well-resourced environment
for the development of research skills.
- An active
seminar
program that brings distinguished scientists from Australia and
overseas to JCU is another unique feature of the Biochemistry
Department, and the honours and graduate students benefit immensely
from this activity.
- The
Department has a
very strong commitment to research and the students who have completed
honours have had no difficulty in finding employment or Ph.D. positions
at JCU or other campuses.
|
WHAT
IS HONOURS?
The aim of an Honours degree is to develop and assess the ability of a
student to undertake independent research. Above all, the Honours
degree program provides training in research skills. Attendance at the
CGC seminars, laboratory based mentorship, regular meetings with the
Honours coordinator, assignments relevant to research goals and
professional development, and the advice of academic and research
staff, support this training. Honours students are traditionally
required to complete a thesis, which functions as an essential test of
the candidate’s capacity to be trained as a scholar and a researcher.
There are many different
reasons why students take the Honours year: you may be contemplating an
academic career, you may wish to improve your employment prospects, you
may wish to complete a particular piece of research, or you may do
Honours because it is considered the 'right' thing to do. It is
important that you identify your reasons for participating in this most
demanding academic program. In terms of a career, an Honours degree is
a more prestigious degree than a pass degree and in many cases it
qualifies people to start employment on a higher pay scale. A first
class Honours degree is a compulsory prerequisite for winning most
competitive scholarships to do a higher degree.
Honours qualifies a person
for normal membership of professional bodies such as Australian Society
for Medical Research, Australasian Society for Immunology and The
Genetics Society of Australia, Australian Society for Biochemistry and
Molecular Biology, and The Australian and New Zealand Society of
Developmental Biology. Honours is also the principal prerequisite for
entry to higher degrees such as the Masters and PhD. It must be
stressed that Honours is not simply a precursor to a PhD. It is also an
interesting and highly rewarding year of study prized by employers who
seek to employ people with a
demonstrated capacity for independent thought and research. It is a
qualification that improves one’s earning potential and opportunities
for promotion. Therefore, every student should contemplate doing
Honours.
To
download the Honour in Biochemistry handbook, click here.
PLANNING
AN HONOURS PROJECT:
The Honours year forms a transition period between the didactic style
of undergraduate study and the self-motivated, mentor-guided
study of the postgraduate. Honours projects there therefore in part
determined by the interests of the individual students and you are
requested to speak with potential supervisors regarding potential
projects. It is particularly useful for prospective students to talk to
as many staff members as possible so that an informed decision can be
made regarding the choice of project(s). Please note that positions
will be allocated on the basis of merit and discussions that you hold
with the prospective supervisor.
APPLYING
FOR AN HONOURS PROJECT:
Candidature for honours in Biochemistry, Molecular Biology or Genetics
requires successful completion of a full major in Biochemistry with
grades of at least a credit average. Under exceptional circumstances
students not reaching these criteria may be able to negotiate a
position. They should confirm the support of a potential supervisor
before contacting the Honours Coordinator Dr Bill Leggat.
After discussions with prospective
supervisors, students intending to complete honours in Biochemistry and
Molecular Biology should submit a copy of the application form below
either by email or in hard copy to Bill Leggat by the
1st November.
THE
ROLE OF THE SUPERVISOR:
Good supervision is usually essential to a successful Honours degree,
although there is no set formula for how this supervision should be
done. The variation derives primarily from the nature of the student,
his or her willingness to engage in independent research combined with
the sense of need to report on progress and/or seek guidance. The
structure of supervision follows a general pattern:
• Initial discussion of potential
thesis topics and general advice on the study skills associated with
independent research.
•
Determination of the topic and suggestions for reading.
•
Reporting on research done, sources identified and ideas for the thesis.
•
Modification of the thesis topic if necessary.
•
Preparation of thesis plan, structure of chapters and writing schedule.
• The
supervisor attending whenever possible a student’s work-in-progress_
presentations during the year.
• The
supervisor submitting a report on the student's progress to the
Discipline Honours coordinator at the end of the first semester of
full-time enrolment and first year of part-time enrolment.
• The
student submitting a progress report to the Discipline Honours
coordinator at the end of the first semester of full-time enrolment and
first year of part-time enrolment identifying any issues that may have
arisen concerning supervision.
• The
supervisor reading and commenting on draft thesis chapters and/or whole
draft thesis.
• The
supervisor checking final draft for corrections, format, style, etc.
The requirement in the Discipline of Biochemistry for supervisory
contact is one hour per fortnight (or 30 minutes/week) over the whole
academic year. This time is best utilised according to the needs of the
student as these are worked out in consultation with the supervisor.
Some students feel they simply must touch base on a short weekly basis,
while others prefer a less frequent supervisory session during the year
with more intensive hourly meetings towards the end. Critically,
supervisors cannot always be available when students want them to be.
The best arrangement is to determine early on a suitable time for both
parties and to stick to that time as best as one can, with the
flexibility of mutually changing the arrangement if either or both
party feels the need.
If a student misses appointed supervision sessions,
it is not up to the supervisor to make up the time. Nor is a supervisor
required to chase up a student for absenteeism. The onus is on the
student and it is designed in this way to reflect a student’s capacity
for independent scholarship. However, if a supervisor unreasonably
fails to meet his or her commitment to a student, the student must
immediately raise the matter with the Honours coordinator, who may
refer the issue to the Head of Discipline or Head of School.
A staff member who will be
away during the year is usually not expected to supervise, especially
if they are away in the second half of the year when theses are written
and submitted. Honours supervision is part of an academic’s teaching
load, which includes undergraduate teaching and postgraduate
supervision. As a result of variations in this load, some academics do
more Honours supervision than others. One cannot assume, therefore,
that one will have the supervisor of choice. Students can contact a
lecturer to discuss the possibility of supervision. However, the
allocation of supervisors is not done on a “first-come first serve”
basis, but must wait until the members of each discipline meet at the
beginning of the year to make an equitable allocation of workload.
THE
ROLE OF THE HONOURS
COORDINATOR:
The coordinator is responsible for the following:
• Inducting students into Honours and
going through the contents of the Honours Handbook
•
Teaching at least one of the Discipline seminars.
•
Overseeing the progress of each student through liaising with the
supervisors and collecting the progress reports.
•
Ensuring the appropriate allocation of supervision
• Dealing
with any issues that may arise between supervisor and student
All student queries of a general nature that cannot be addressed to the
supervisor in the first instance should be addressed to the
coordinator. In addition, the coordinator is responsible for creating
and holding a confidential file on each student that contains the
student's contact details, supervisor's name and a print-out of the
student's academic record. The transcript includes the notation of the
numerical marks the student has achieved in each subject that has
counted towards the Discipline Major. This last requirement stems from
the fact that a number of Australian universities use these marks to
assist in ranking students for scholarship applications. The practice
derives from the traditional English Honours system where the Level 3
marks in the discipline one "read" at university are counted as a
component of the Honours mark. JCU does not do this and instead
requests the Level 3 GPA. However, other universities do make the
request and it is much easier if the marks are recorded from School
assessment records in advance.
The
Honours
Coordinator in Biochemistry is Bill Leggat.
To
download the Honours in Biochemistry handbook, click here.
HONOURS
TIMETABLE:
|
Beginning January 2009 |
Beginning
July 2009 |
|
| Apply to honours coordinator |
14.11.09
|
15.5.09 |
Apply to honours coordinator |
| Start |
2.2.09 |
6.07.09 |
Start
|
| Introductory seminar |
19.3.09 |
20.8.09
|
Introductory seminar |
| Literature review due |
31.3.09 |
1.9.09
|
Literature review due |
| Mid year seminar |
9.7.09 |
18.2.10
|
Mid year seminar |
| Assignment due |
11.8.09 |
2.3.10
|
Assignment due |
| Poster due |
16.10.09 |
23.4.10
|
Poster due |
| Cessation of lab work |
21.10.09 |
27.4.10 |
Cessation of lab work |
| Thesis due |
10.11.09 |
18.5.10
|
Thesis due |
| Final seminar |
17.11.09 |
25.5.10
|
Final seminar |
| Oral defence |
23.11.09 |
27.5.10
|
Oral defence |
| Release of grades |
24.11.09 |
28.5.10
|
Release of grades |
Introductory seminars
Early in the first
semester students will be required to give a 15 minute informal talk
about their chosen research project; this talk, which will form no part
of the final assessment, should cover the basic aims of the project and
the approach to be employed. It is hoped that these talks, and the
ensuing discussions, may result in constructive suggestions and new
ideas for the further development of the projects.
Attendance at Honours Meetings and Research Seminars
Attendance at the
honours meetings and CGC research seminars is mandatory. The honours
meetings are a forum for the cohort of students to present their work
to each other as it progresses, to gain experience and confidence in
talking about science, and (if necessary) to raise any practical or
personal issues. These meetings will be held at least fortnightly, and
will take the format of a first general gossip about laboratory
matters, a short research presentation by one student, followed by a
journal club presentation by another student. For your journal club
presentation(s), you should select a recent research article that is
both topical and of general interest. You must get the honours
coordinator to confirm that the article is suitable for a presentation,
and you should circulate copies of the article to the other students at
least one week before the talk. All students must read the articles
before the meetings, so that anyone can be asked to explain data or
figures from the paper.
Health and Safety
All honours students are required to adopt safe working procedures.
There will be a full day biosafety course early in the first semester.
The full details of this will be provided by the Honours coordinator
and all honours students must attend this course. A radiation safety
course will be conducted on about the same time and again this is
compulsory for all honours students. Information on this will be posted
to all students when the arrangements are finalised by the University
Radiation Safety Committee.
ASSESSMENT:
Assessment of honours is based on the following components:
| 10% |
Literature
review
|
| 5% |
Assignment
(2 page Ph.D. funding proposal) |
| 5% |
Poster
|
10%
|
Final
seminar
|
| 15% |
Supervisor's
mark and lab book assessment |
| 45% |
Thesis
|
10%
|
Oral defence (viva) |
Please note that
attendance at the CGC seminar series is compulsory and content
presented may be examined.
Format for literature review:
The literature review should
cover the literature relevant to the research project to be conducted
by the student. It should contain references to papers describing
original work, not just to reviews, and should include descriptions of
some of the theory of the techniques to be used in the research
project. Diagrams are likely to assist in the presentation of the
material and particular care should be taken to avoid plagiarism. The
literature review should resemble the introduction of a thesis and
should include the aims of the research project. It should consist of
no more than 4,000 words, and include
Background (literature review, hypotheses and aims) and References
sections. Due to the breadth of subjects presented, assessment will be
made on scientific criteria; an excellent literature review will be one
in which:
• Background provides a literature review of
sufficient depth to justify project
• Appropriate citation of literature
• Adherence to academic citation format
• One or more hypotheses or aims is explicitly stated
• The rationale for the work is provided
• High standard of general presentation
• Adequate binding
Submit 5 hard copies and one electronic copy to the honours coordinator.
Format for assignment:
Research scientists must
apply for funding from bodies such as the ARC (Australian Research
Council) or NH&MRC (National Health & Medical Research Council)
as well as other government and non-government bodies. The
process is highly competitive and it is important that you gain an
understanding of how this works if you go on to pursue a career in
research. Realistic expected outcomes, relevance, profitability, good
science and excellent communication will affect the success of grant
applications.
As part of honours you are
required to write a research proposal for a three year PhD project ($15
000 /year). It may be an extension of your honours project but it does
not have to be. It must be carefully thought out, precise, concise and
specific and it will be marked critically, as a real grant application
would be.
Format (modified from NH&MRC NOI)
• Scientific Title - Ensure the title of your project
reflects the topic, area and type of research to be undertaken
• Aims - Describe the aims of your project (maximum
of three aims) and include your hypothesis.
• Background - Describe the background of your
proposal taking into consideration the minimum information that is
required for the panel to understand your research proposal.
• Research Plan - A short and concise plan of your
research
• Significance - Should describe clearly the impact
of your proposed project.
Marking Criteria
1) Significance
Would the project, if successfully carried out, make an original and
important contribution to a scientific discipline in the field of
biochemistry, molecular biology, cell biology or genetics?
2) Approach
Is the experimental approach, model system, experimental methods and
data analyses proposed well conceived and appropriate to the aims and
hypotheses of the project?
3) Feasibility
Could the proposed project be accomplished by a single student within a
3 year timeframe with access to materials and resources costing less
than $15,000 per year? Could the project be performed with currently
available equipment and infrastructure at James Cook University?
4) Presentation
Is the assignment of two (2) A4 pages or less in length, written in 12
point Times New Roman Font, single-spaced, with margins no less than
2cm? Is the assignment clearly written and presented with a logical
flow of information that includes background, hypotheses, aims and a
research plan?
Laboratory book assessment:
Laboratory books are
expected to be kept up to date, provide an accurate record of methods,
work performed and results, and to conform to the standards required
for the work within them to withstand patent defense. Specifically:
• Entries are to be dated
• Errors are not to be overwritten, covered over,
deleted or removed, but are to be ruled out,
corrected, dated and signed
• Pages are to be numbered
• Methods should be in sufficient detail to allow
replication by a third party
• Blank spaces are to be ruled out
Your supervisor will provide a mark based upon your laboratory book but
also your conduct and application throughout the year. This mark will
reflect how effectively you have functioned in a laboratory environment
and be based upon:
• Your general laboratory skills
• Your ability to interpret data, design and conduct
experiments
• Your ability to effectively communicate your
results to your supervisor and other members of the laboratory where
appropriate
• Your punctuality for meetings and other lab events
• Your general contribution to the laboratory, for
example in lab meetings or lab maintenance
• Your professional conduct as a scientist, including
how you interacted with other members of the lab
Format for final seminar:
Twenty minute Powerpoint™
presentation and five minutes for questions. Due to the breadth of
subjects presented, assessment will be made on scientific criteria; an
excellent seminar will be one in which:
• One or more hypotheses or aims are explicitly stated
• The rationale for the work is provided
• Data are clearly presented
• Logic is sound
• Conclusions are justified by the data presented
• Future directions or final conclusion of the study
are/is indicated
Format for poster:
On the day of the viva voce
examination, candidates will be required to present a poster on their
research findings. The poster will be assessed in the days before the
oral defence on:
1. Content - scientific content, critical assessment
of the topic
2. Presentation - visual clarity and conciseness
3. Questions - understanding of questions and the
ability and skill in response.
Posters should be no larger than 1.0 x 1.5m and clearly presented. They
should contain a brief abstract, methods and results and a conclusion.
As a general rule, they should not contain more than 750 words of text,
but are expected to conform to the standards of the particular
subdiscipline in which the student is studying. Students should seek
guidance from their supervisors in this regard. It is advisable that
you look at those posters that are present around the building and use
these as a guide for your poster. Posters should be printed on A0 size
paper (or equivalent) and be laminated. The poster will be assessed by
a number of academics and examined on clarity of presentation and
quality of the research. Remember to make sure that the text and
figures are easily read from a distance.
Format for thesis:
Between 10,000 and 20,000
words, consisting of Background (literature review, hypotheses, aims),
Methods, Results, Discussion and Conclusions, References. Due to the
breadth of subjects presented, assessment will be made on scientific
criteria; an excellent thesis will be one in which:
• Background provides a literature review of
sufficient depth to justify the project
• Appropriate citation of literature
• Adherence to academic citation format
• One or more hypotheses or aims is explicitly stated
• The rationale for the work is provided
• Methods described with sufficient clarity to allow
replication
• Data are clearly presented
• Logic is sound
• Conclusions are justified by the data presented
• Future directions or final conclusion of the study
are/is indicated
• High standard of general presentation.
• Adequate binding
Assessment Criteria
• The development of research aims and outcomes
• Analysis and presentation of results
• Use of literature in the thesis
• Originality of the thesis and quality of argument
• Quality and standard of illustrations, tables and
overall production
• Overall style and accuracy of the thesis
• Overall understanding of the project and methods
used during completion of the project
You must submit 5 bound copies and one electronic copy to the honours
co-ordinator.
Oral defence of thesis:
The poster will be used as a
centre point for discussion. Staff will have already read it, but would
appreciate a brief reminder of its major points. You will then be asked
questions related to your work, but other scientific issues may be
raised, such as those that have arisen from work presented in honours
meetings and the CGC seminar series.
Guide To grades:
The following is a broad guide to what the thesis grade and overall
Honours grade means. The points relate to the thesis quality and the
general statement relates to the overall assessment of the student’s
potential for further study.
Class 1 (HD, 85-100%)
• Outstanding command of expression and logical
argument
• Coherent use of research sources and data
• Critical evaluation of extant literature
appropriate to the topic
• Strong sense of issue in relation to the discipline
• Command over a particular theoretical approach
• Originality of project and ideas
• Excellent overall production including tables,
illustrations, etc.
Upper H1s (90-94 &
95-100)
Display excellence in all these areas.
Lower H1s (85-87 & 88-89)
Are still excellent, but less well balanced in overall quality. All
Class 1 students are considered to be capable of pursuing a higher
research degree.
Class 2A (D, 75-84%)
Class 2A students are considered capable of pursuing a higher degree.
• Well-written, logically argued and well-structured
• Good use of sources and data, but a key example is
missing
• Strong sense of the literature and good integration
with text
• Sense of issue and demonstrated knowledge of
discipline
• Attempt to grasp an appropriate theoretical approach
• Evidence of original thought but could be better
integrated
• Overall good production
Class 2B (C, 65-74%)
Overall, a H2B student is capable of pursuing postgraduate work, but
would be encouraged to complete a Masters degree before attempting a
PhD.
• Generally good written expression and organisation
of thesis
• Adequate coverage of extant literature, but
noteworthy omissions
• Intimations of relevance of topic to the discipline
• Weak understanding of appropriate theory or use of
inappropriate theory
• Little evidence of originality of thought
• Solid overall production
Class 3 (P, 50-64%)
While a student_s undergraduate degree may show evidence of suitability
for Honours, their performance in Honours may raise doubts about their
potential for higher degree research. Students awarded an H3 should
consider pursuing a coursework Masters if they want to do further
study.
• Not well written with flaws in expression and
logic, needs editing
• Weak coverage of extant literature with glaring
omissions
• Weak understanding of research methods and analysis
of data
• No strong sense of overall issue and relevance to
the discipline
• Lacking in originality and superficial in
interpretation
• Inadequate grasp of theoretical approaches
• Poor presentation of data
Fail (N, <50%)
• Poorly and hurriedly written, badly integrated
• Serious flaws in the coverage of extant literature
• Misunderstanding of key concepts
• Misunderstanding of research techniques and data
analysis
• Inability to demonstrate the finding of the
research in a clear manner
PENALTIES:
Late
submisson
Escalating penalties will be
imposed for submission of an honours thesis or assignments after the
date specified in the honours guide. The formula of the penalty
is “Percentage Reduction = 1 x days squared” including part-days,
weekends and public holidays. Extensions may be granted for genuine
circumstances at the discretion of the honours co-ordinator and head of
discipline.
In extenuating circumstance extensions for submission of work MAY be
granted, if in the opinion of course co-ordinator and head of
discipline the circumstances have significantly affected the students
ability to perform their study. If you are contemplating a request for
an extension you should consult the honours co-coordinator as soon as
possible, requests for extensions must be made at least 2 weeks prior
to the due date.
Medical conditions which have affected your work may be used for an
extension request however the honours co-ordinator and academics
reserve the right to not grant an extension, or grant an extension for
only part of the period of illness, if they feel the student was able
to undertake some or all of their honours study during their illness.
Original medical certificates should be submitted to the honours
co-ordinator within 1 week of the date in which you return to study.
Medical certificates MUST include as a minimum:
i. The dates of illness
ii. The date you were seen by the doctor (this must be in the period
you were ill or within 1 week of the illness)
iii. Within the bounds of patient privacy, clearly indicate which
duties that you are able to complete and those which you can not (e.g.
The patient was unable to perform laboratory duties due to a broken leg
but was able to use a computer). A general statement that you were
unable to perform your studies will not be accepted..
Plagiarism
Plagiarism means "publishing
borrowed thoughts as your own" (OED). It has been defined by the
university for disciplinary purposes as "Reproduction without
acknowledgement of another person's words, works or thoughts (including
a fellow student's) from any source... The definition of words, works
or thoughts includes such representations as diagrams, drawings,
pictures, objects, text artistic works and other such expressions of
ideas." Plagiarism is a serious offence and will not be tolerated in
any form - in the scientific community, people lose jobs if they are
found guilty of plagiarism. When you write your literature review,
assignment and thesis (and scientific papers), you are obliged to
express all of the material in your own words; read the background
material, think about what it means and say what needs to be said in
your way. If you use sentences from the background material (or from
anywhere else) without acknowledging that the sentence is not yours by
putting it in quotation marks (as well as including a citation at the
end of the sentence), you are guilty of plagiarism. Note that this kind
of device is hardly ever used in scientific writing, so use it
sparingly in your own work; in general you will receive better marks if
you use your own words on all occasions.
You may not copy any
published (or unpublished) work of others without acknowledging that
the sentence is not yours by putting it in quotation marks (as well as
including a citation at the end of the sentence). If in any assessable
material a student uses a single sentence that is demonstrably not
their own, that student will be penalised severely.
To
download the Honours in Biochemistry handbook, click here.
OTHER
LINKS:
Comparative
Genomics Centre, James Cook
University, Key words: Autoimmune diabetes, Type 1 diabetes mellitus,
childhood
diabetes, lupus, systemic lupus erythematosus, haemolytic anaemia,
hemolytic
anemia, Coombs' test, antinuclear antibodies, renal failure,
glomerulonephritis, gastritis, type A gastritis, pernicious anemia.