TREAD-research-areas

TREAD-research-areas

Research Areas:

The broad areas of research include,

  • Diabetic foot ulcers: prevention and management.

  • Micro and macrovascular complications of diabetes

  • Diabetes management

  • Lipid disorders associated with metabolic syndrome

Our ongoing studies include

1. Clinical Research

  • Understanding the effects of DPP4 inhibitors in diabetes management

  • Identification of risk factors associated with development of diabetic foot ulcers

  • Novel ways of management of diabetic foot ulcers

  • Risk factors associated with development of diabetic foot ulcers

  • Prevalence of lower limb amputation in the North Queensland region

2. Clinical trials

  • GIED study: examining the role of vildagliptin on IL-6 regulation in diabetic patients with foot ulcers

  • TECOS (Multicentre international study) – co investigator- Using sitagliptin with metformin in type 2 diabetes clients

  • LEADER- Principal investigator- Liraglutide in patients with type 2 diabetes with cardiovascular disease

  • AT.Lantus- Principal investigator- Comparing insulin regimens in complicated type 2 diabetes clients

  • ELIXA: Evaluation of lixisinatide in acute coronary syndrome

  • LANDSCAPE: Comparison of insulin Glargine/Glulisine with mixed insulin

3. Basic science research:

  • The role of oxidised lipids in atheroma formation and metabolic syndrome

  • Understanding macrophage biology associated with atherogenesis

  • Novel markers for identifying cardiovascular risk factors

4. Townsville TeleDiabetes and TeleEndocrinology Network

  • To improve the efficiency and effectiveness of care for persons with diabetes at participating clinics through improved clinical triage, workflow, and intervention using information and alerts from telemonitoring

  • To empower patients to take a greater role in the management of their diabetes

  • To improve clinical outcomes and satisfaction of patients enrolled in telemonitoring

Overall, research at the TREAD is directed towards improved understanding and novel treatments for diabetic foot ulcers and metabolic syndrome.