Medicinal Chemistry – Synthesis of Bioactive Compounds

Medicinal Chemistry – Synthesis of Bioactive Compounds

Medicinal Chemistry – Synthesis of Bioactive Compounds

A/Prof Michael Oelgemöller, Dr Mark Robertson

This research includes the synthesis of bioactive molecules as well as enabling technologies in order to facilitate this synthesis. The medicinal chemistry team is developing synthetic pathways to novel antibiotic, anti-epileptic, anthelminthic, antimalarial, cardiovascular, anesthetic and anticancer target molecules. The enabling technologies examined include microwave assisted synthesis, flow chemistry, photochemistry and parallel synthesis. The team is furthermore experienced in computer aided drug design with expertise in molecular dynamics, docking studies and inspection based, de novofragment based and ligand based designs. Within the new Science Place building, the group occupies modern laboratories for organic synthesis, separation/purification and molecular characterization.