Developing a web tool for animal sequencing data analysis

Developing a web tool for animal sequencing data analysis

Advisor/s

A/Prof Ulf Schmitz

College or Research Centre

College of Science & Engineering

Summary of Project

Due to the dramatic reduction in cost for next-generation sequencing, RNA sequencing (RNA-seq) has become a routine research tool and hence large amounts of RNA-seq data have been deposited in public repositories such as NCBI’s – Sequencing Read Archive (SRA). Although these freely available data have vast potential for addressing questions that would not be possible in individual studies most of these data remained untapped mainly due to a lack of computer infrastructure and computer programming skills needed to analyse thousands of gene expression data.

To overcome this, we will build a web-based platform that not only stores thousands of uniformly processed gene expression data but also allows the execution of standard bioinformatics analyses, such as clustering, correlation and co-expression analysis, dimensionality reduction, etc.) and the generation of publication-ready graphs with just a few clicks.

Key Words

bioinformatics; R Shiny; RNA sequencing; web resources

Would suit an applicant who

is interested in bioinformatics, software development, transcriptomics data analysis. Some bioinformatics skills (incl. R programming) would be very helpful.

Updated: 04 Aug 2022