Using rodent models to identify treatments for peripheral artery disease

Title of Project

Using rodent models to identify treatments for peripheral artery disease

Name of Advisor/s

Jonathan Golledge

College

College of Medicine & Dentistry

Summary of Project

Peripheral artery disease (PAD) is a common disorder in which blood supply to the extremities (commonly lower limb) is reduced due to an accumulation of atherothrombosis within the arteries. Currently surgery is a mainstay of PAD treatment, although this is costly and not always effective. There is a need to identify non-surgical alternatives therapies to treat patients. We offer pre-clinical projects assessing the therapeutic potential of re-purposed drugs and/or dietary interventions for PAD using a novel rodent model which was developed by our team.

Key Words

Peripheral artery disease; rodent model; Therapy

Would suit an applicant who

Has a background in:

Biological/Biomedical sciences

Working with experimental animals