Graduate Research School For Candidates Prospective Candidates Available Projects Developing new ways to predict outcomes for patients with peripheral artery disease

Developing new ways to predict outcomes for patients with peripheral artery disease

Title of Project

Developing new ways to predict outcomes for patients with peripheral artery disease

Name of Advisor/s

Jonathan Golledge

College

College of Medicine & Dentistry

Summary of Project

Peripheral artery disease (PAD) is an umbrella term for a range of stenosing (blocking) or aneurysmal (weakening) disorders within the arteries outside the heart. Patients with PAD are at increased risk of major cardiovascular events (e.g. stroke and heart attack), and may require multiple surgeries to manage their disease. Currently it is difficult to predict outcomes for PAD patients and there is a need to identify factors contributing to progression and outcome of their disease. This project will employ statistical and biochemical analyses to build risk-prediction models to identify major determinants of outcome for PAD patients, with a view to personalising healthcare for these individuals.

Key Words

Peripheral artery disease; biomarker; outcome prediction; bioinformatics

Would suit an applicant who

Has a background in:

Bioinformatics/biostatistics

Biochemical assays to measure circulating markers (e.g. ELISA)