Graduate Research School Available Projects Optimal drug combinations to combat regional tuberculosis isolates
Optimal drug combinations to combat regional tuberculosis isolates
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Title of Project
Optimal drug combinations to combat regional tuberculosis isolates
Advisor/s
Emma McBryde
College or Research Centre
College of Medicine & Dentistry; Australian Institute of Tropical Health and Medicine
Summary of Project
Drug resistance in Mycobacterium tuberculosis (Mtb) may prove an insurmountable hurdle in TB control. After a decades long wait, new drugs have finally reached the market and these must be used judiciously in order to prevent resistance emergence and failure of therapy. New data on clinical impact and in vitro efficacy our now available, and these data will be modelled in this project to ascertain the impact of different combinations of anti-mycobacterial agents.
Key Words
infectious diseases; pharmacokinetics; tuberculosis; pharmacodynamics; mathematical modelling
Would suit an applicant who
Has a background in mathematics or other quantitative discipline Has an interest in pharmacology or applying mathematics to a pkpd model Has an interest in international health
Updated: 03 Apr 2020