Townsville melanoma prevention study

Townsville melanoma prevention study

Title of Project

20+ year follow-up of cohort examined for pigmented moles in early childhood

Name of Advisor/s

Simone Harrison

College

College of Public Health, Medical & Veterinary Science

Summary of Project

Queensland has the highest rates of melanoma globally, and the number of pigmented moles developing in childhood is the most important phenotypic risk-marker for identifying those at greatest risk of developing melanoma. This project involves following up cases and control subjects from an RCT of sun-protective clothing conducted in Caucasian 0-3 year-old children attending participating daycare centres in Townsville 1999-2005 and re-examining their skin for pigmented moles to see if the effect of this successful intervention was sustained over time. We plan to re-examine subjects for MN (common and atypical), collect sun-exposure information (via questionnaire; silicone casting & UVR-dosimeters (incl pre- and post-sun exposure for behavioural intervention component) and relevant disease history (excised MN, diagnosis of cutaneous melanoma (CM), and family history of CM) as well as collecting saliva for genotypic assessment in conjunction with our collaborators.

Keywords

Melanoma; melanocytic naevus; naevi; epidemiology; UV; sunlight; sunburn; childcare; clothing; photoprotection; behaviour; prevention; intervention; RCT.

Would suit an applicant who

This project is suitable for a PhD student (preferably with a medical, nursing or public health background). Interested HDR eligible candidates should contact simone.harrison@jcu.edu.au