Title of Project
20+ year follow-up of cohort examined for pigmented moles in early childhood
Name of Advisor/s
College of Public Health, Medical & Veterinary Science
Summary of Project
Queensland has the highest rates of melanoma globally, and the number of pigmented moles developing in childhood is the most important phenotypic risk-marker for identifying those at greatest risk of developing melanoma. This project involves following up cases and control subjects from an RCT of sun-protective clothing conducted in Caucasian 0-3 year-old children attending participating daycare centres in Townsville 1999-2005 and re-examining their skin for pigmented moles to see if the effect of this successful intervention was sustained over time. We plan to re-examine subjects for MN (common and atypical), collect sun-exposure information (via questionnaire; silicone casting & UVR-dosimeters (incl pre- and post-sun exposure for behavioural intervention component) and relevant disease history (excised MN, diagnosis of cutaneous melanoma (CM), and family history of CM) as well as collecting saliva for genotypic assessment in conjunction with our collaborators.
Melanoma; melanocytic naevus; naevi; epidemiology; UV; sunlight; sunburn; childcare; clothing; photoprotection; behaviour; prevention; intervention; RCT.
Would suit an applicant who
This project is suitable for a PhD student (preferably with a medical, nursing or public health background). Interested HDR eligible candidates should contact email@example.com