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Current studies

QRC-PVD is currently recruiting participants to take part in clinical research relating to Peripheral Vascular Disease. We are looking for suitable participants for our ongoing Peripheral Vascular Biobank and active clinical trials.

If you are interested in participating or want to find out more about clinical research studies, explore the relevant project summaries below.

QRC-PVD Peripheral Vascular Biobank

Biobank is a collection of high quality human blood, tissue samples and clinical information. Blood contains chemicals that can provide scientists with a greater understanding of how diseases develop and progress. Studying these chemicals can potentially help with earlier diagnosis and treatment of disease or provide new targets for treatment.

QRC-PVD Research Study - an Innovative prograM to Prevent diAbetes-related foot ComplicaTions (IMPACT)

The purpose of this study is to gather information about patient perspectives of living with Diabetic Foot Disease (DFD) and related complications and clinician perspectives on preventing these complications. If you have diabetes and a history of diabetes related leg or foot problems, or are involved with the care of patients with a history of diabetic leg or foot problems, your experiences and contributions to this study would be invaluable.

QRC-PVD Clinical Trial - Metformin for Treating Peripheral Artery Disease-Related Walking Impairment (MERIT)

Peripheral Artery Disease (PAD) is a blockage and narrowing of arteries which leads to poor circulation in the legs. A number of research studies suggest a drug called Metformin may improve patients' physical activity.

Past studies

Once our clinical trials have been finalised, participants will be provided a copy of the overall outcomes. Information about the clinical trial will also be available on this website for participants to refer to. Results are available for the following research studies:

QRC-PVD Clinical Trial - Telmisartan in the Management of Abdominal Aortic Aneurysm (TEDY)

This study aimed to see whether a medication, Telmisartan, can reduce the growth of small (35-49cm) abdominal aortic aneurysms (AAA).

QRC-PVD Clinical Trial - Inositol in the Management of Abdominal Aortic Aneurysm (IMAGEN)

This study aimed to test the effectiveness of a dietary supplement, Inositol, in reducing the growth of small (30mm or over) abdominal aortic aneurysms (AAA). Inositol is a dietary supplement which appeared to slow growth of AAA in laboratory experiments.

QRC-PVD Clinical Trial - Fenofibrate in the Management of Abdominal Aortic Aneurysm (FAME)

This study aimed to test the effectiveness of a two-week course of a pharmaceutical, Fenofibrate, before surgery to repair Abdominal Aortic Aneurysms (AAA).

QRC-PVD Clinical Trial - Fenofibrate in the Management of Abdominal Aortic Aneurysm Study 2 (FAME2)

This study aimed to test the effectiveness of a 24-week course of a pharmaceutical, Fenofibrate, before surgery to repair Abdominal Aortic Aneurysms (AAA).

QRC-PVD Clinical Trial - Brief Behavioural Counselling Intervention for Peripheral Artery Disease (BIP)

This study involves health workers delivering brief behavioural counselling sessions with an aim to improve self-management of patients with blocked leg arteries. The results of this study will help develop new treatments, increase understanding of the condition and improve healthcare.