QRC-PVD Clinical Trial - Fenofibrate in the Management of Abdominal Aortic Aneurysm (FAME)

This study aimed to test the effectiveness of a two-week course of a pharmaceutical, Fenofribrate, before surgery to repair Abdominal Aortic Aneurysms (AAA).

Recruitment Status

Recruitment closed


Aneurysms slowly expand overtime at a rate of 2-4mm per year. The only treatment available is surgical intervention. No medications have been effective in slowing the growth rate of AAA. Previous studies found possible protective results in cholesterol lowering medication like Fenofribrate.

Consenting participants attended our study centres a minimum of two times over four weeks. Forty-two participants enrolled in our study, which took place over six years.


The data collected from this study is still being analysed. Results will be published in peer-reviewed journal articles and communicated to participants.

See also:

Rowbotham, S.E., et al. (2017) Fenofibrate in the management of AbdoMinal aortic anEurysm (FAME): study protocol for a randomised controlled trial. Trials, 18:1 [doi:10.1186/s13063-016-1752-z]