QRC-PVD Clinical Trial - Fenofibrate in the Management of Abdominal Aortic Aneurysm (FAME)

This study aimed to test the effectiveness of a two-week course of a pharmaceutical, Fenofibrate, before surgery to repair Abdominal Aortic Aneurysms (AAA).

Recruitment Status

Recruitment closed

Background

Aneurysms slowly expand overtime at a rate of 2-4mm per year. The only treatment available is surgical intervention. No medications have been effective in slowing the growth rate of AAA. Previous studies found possible protective results in cholesterol-lowering medication like Fenofibrate.

Consenting participants attended our study centres a minimum of two times over four weeks. Forty-two participants enrolled in our study, which took place over six years.

Outcomes

The data collected from this study is still being analysed. Results will be published in peer-reviewed journal articles and communicated to participants.

See also:

Rowbotham, S.E., et al. (2017) Fenofibrate in the management of AbdoMinal aortic anEurysm (FAME): study protocol for a randomised controlled trial. Trials, 18:1 [doi:10.1186/s13063-016-1752-z]