Graduate Research School Available Projects Systems immunology and multi-omics approaches to understand protective immunity to human malaria
Systems immunology and multi-omics approaches to understand protective immunity to human malaria
- Aboriginal and Torres Strait Islander in Marine Science
- Courses
- Future Students
- Current Students
- Research and Teaching
- Partners and Community
- About JCU
- Reputation and Experience
- Celebrating 50 Years
- Academy
- Anthropological Laboratory for Tropical Audiovisual Research (ALTAR)
- Anton Breinl Research Centre
- Agriculture Technology and Adoption Centre (AgTAC)
- Living on Campus
- How to apply
- Advanced Analytical Centre
- Alumni
- AMHHEC
- Aquaculture Solutions
- AusAsian Mental Health Research Group
- ARCSTA
- Area 61
- Association of Australian University Secretaries
- Australian Lions Stinger Research
- Australian Tropical Herbarium
- Australian Quantum & Classical Transport Physics Group
- Boating and Diving
- JCU-CSIRO Partnership
- Employability Edge
- Clinical Psychedelic Research Lab
- Centre for Tropical Biosecurity
- Career Ready Plan
- Careers at JCU
- Careers and Employability
- Chancellery
- Centre for Tropical Bioinformatics and Molecular Biology
- CITBA
- CMT
- CASE
- College of Business, Law and Governance
- College of Healthcare Sciences
- College of Medicine and Dentistry
- College of Science and Engineering
- CPHMVS
- Centre for Disaster Solutions
- CSTFA
- Cyber Security Hub
- Cyclone Testing Station
- The Centre for Disaster Studies
- Daintree Rainforest Observatory
- Defence
- Discover Nature at JCU
- Research Division
- Services and Resources Division
- Education Division
- Elite Athletes
- eResearch
- Environmental Research Complex [ERC]
- Estate
- Fletcherview
- Foundation for Australian Literary Studies
- Gender Equity Action and Research
- General Practice and Rural Medicine
- JC 'U' Orientation
- Give to JCU
- Governance
- Art of Academic Writing
- Art of Academic Editing
- Graduate Research School
- Graduation
- Indigenous Education and Research Centre
- Indigenous Engagement
- Indigenous Legal Needs Project
- Inherent Requirements
- IsoTropics Geochemistry Lab
- IT Services
- International Students
- Research and Innovation Services
- JCU Eduquarium
- JCU Heroes Programs
- JCU Webinars
- JCU Events
- JCU Global Experience
- JCU Ideas Lab
- JCU Job Ready
- JCU Motorsports
- JCU Prizes
- JCU Sport
- JCU Turtle Health Research
- Language and Culture Research Centre
- CEE
- LearnJCU
- Library
- Mabo Decision: 30 years on
- MARF
- Marine Geophysics Laboratory
- New students
- Off-Campus Students
- Office of the Vice Chancellor and President
- Virtual Open Day
- Orpheus
- Open Day
- Outstanding Alumni
- Parents and Partners
- Pathways to university
- Pharmacy Full Scope
- Planning for your future
- Placements
- Policy
- PAHL
- Publications
- Professional Experience Placement
- Queensland Research Centre for Peripheral Vascular Disease
- Rapid Assessment Unit
- RDIM
- Researcher Development Portal
- Roderick Centre for Australian Literature and Creative Writing
- Safety and Wellbeing
- Scholarships
- Contextual Science for Tropical Coastal Ecosystems
- Staff
- State of the Tropics
- Strategic Procurement
- Student Equity and Wellbeing
- Student profiles
- SWIRLnet
- TARL
- TESS
- TREAD
- TropEco for Staff and Students
- TQ Maths Hub
- TUDLab
- Unicare Centre and Unicampus Kids
- UAV
- VAVS Home
- Work Health and Safety
- WHOCC for Vector-borne & NTDs
- Media
- Copyright and Terms of Use
- Australian Institute of Tropical Health & Medicine
Title of Project
Systems immunology and multi-omics approaches to understand protective immunity to human malaria
Advisor/s
Professor Denise Doolan
College or Research Centre
Australian Institute of Tropical Health and Medicine
Summary of Project
We invite applications for a PhD position focused on identifying human host factors that predict immune control of malaria. The project will utilise systems-based immunology and multi-omics approaches to profile the host immune response in controlled infection models of malaria at molecular, cellular, transcriptome and proteome-wide scale. The overall aim will be to develop and apply computational/biostatistical approaches, including network theory and machine learning, which integrate genomics, proteomics, transcriptomics and molecular immunology to improve our understanding of the host-parasite relationship and predict immune responsiveness and parasite control. Molecular signatures of immunity to malaria will inform the development of vaccines, immunotherapies or diagnostic biomarkers. This project will provide an opportunity to be involved in cutting-edge advances integrating diverse fields of high dimensional -omic datasets. It will complement ongoing systems-based and therapeutic development efforts at AITHM directed at malaria and other tropical pathogens. The successful candidate will learn from, and be supported by, a team of researchers in bioinformatics, immunology, molecular sciences and biostatistics. This project is supported by a AITHM funded Stipend Scholarship: $28,000 per annum for three years (full-time study). Further information about this scholarship can be found at https://www.aithm.jcu.edu.au/phd-stipend-scholarship/
Key Words
Malaria; bioinformatics; immunology; vaccine; multi-omics; host-pathogen interaction; R; statistics; sequencing technology
Would suit an applicant who
PhD candidate interested in combining immunology and bioinformatics for advancing malaria therapeutic development.
Updated: 11 Apr 2020