The role of novel genes in muscle growth

The role of novel genes in muscle growth

Advisor/s

A/Prof Lionel Hebbard

College or Research Centre

College of Public Health, Medical & Veterinary Science

Summary of Project

Our focus is to understand the role of novel genes in muscle growth and metabolism, with the view to develop new therapeutic strategies to promote muscle growth and treat sarcopenia. The successful applicant will use bioinformatics of public human HCC data sets to determine the association of specific genes in muscle disease. The function of chosen genes will be determined in mouse and human muscle cell lines using gene ablation techniques and over-expression models. The candidate will learn to perform histology, western blots, genetic analyses, qPCR, muscle injury models and to culture primary myoblasts from murine and human muscles.

Key Words

bioinformatics; myogenesis; sarcopenia; muscle growth; signaling; stem cells; metabolism

Would suit an applicant who

A good science or medical graduate with laboratory experience.

Updated: 23 Feb 2022